Research

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Aged or severely injured skeletal muscle is associated with reduced regenerative capacity and force production. Contributing factors include loss of functional contractile tissue and neuromuscular junctions, heightened inflammation, excessive collagen deposition, and dysfunctional stem cells. On-going projects in the laboratory are aimed at improving the regeneration and function of skeletal muscle following injury, disease or aging. Our research interests include cell and tissue engineering, extracellular matrix based biomaterials, stem cells, immune response, skeletal muscle, and neuromuscular junctions.

 

Funding Sources (Internal):

  • Institute for Drug and Biotherapeutic Innovation Seed Grant (Saint Louis University)

  • Applied Health Sciences Research Grant (Saint Louis University)

  • President's Research Fund (Saint Louis University)

  • Beaumont Faculty Development Fund (Saint Louis University)

  • KEEN Program Transformation Grant (SLU/KEEN)

 

Funding Sources (External):

  • National Institute of Health (NIGMS) 1R15GM129731

  • Department of Defense (PRORP) OR170286

  • National Science Foundation (I-corps)

  • Center for Defense Medicine at Biogenerator (STL)

  • Joint NC NM4R and AR3T Neuromodulation and Regenerative Rehabilitation Funding Program

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